PROTEINPOLYSACCHARIDES OF HUMAN COSTAL CARTILAGE*

The proteinpolysaccharides of human costal cartilage.

Water-soluble proteinpolysaccharides, called PPL, can be extracted from bovine nucleus pulposus in yields of 45%, and from bovine nasal cartilage in yields of 37% of the dry tissue weight. From human costal cartilage only 7% can be extracted. The method used to separate PPL from each of the first two tissues into four distinct fractions separates the PPL of human costal cartilage into four frac...

Proteinpolysaccharides from human articular and costal cartilage.

Comparative fractionation studies of cartilage proteinpolysaccharides.

Proteinpolysaccharides from bovine embryonic rudiments and calf nasal septa were compared by conventional ultracentrifugation in isotonic salt solutions, equilibrium density gradient centrifugation, and free flow electrophoresis. These methods are all suitable for use with large amounts of material and give reliable materials balances. Fractions obtained by any one method could be isolated and ...

Mechanical Characterization of Costal Cartilage

Rib fractures are a common morbidity following automotive crashes. While the rib bones are wellcharacterized, and articular cartilage from joints such as the knee and shoulder has been extensively mechanically characterized, almost no mechanical examination has been performed of the rib-cage costal cartilage. Costal cartilage is a hyaline cartilage, like articular cartilage, but it differs from...

The Action of Hydroxylamine on the Proteinpolysaccharides of Cartilage.

In the native state, the polysaccharides of cartilage act as if they were linked to protein by bonds labile to alkali such as ester bonds. This thought was more or less clearly expressed by Krukenberg (I), Schmiedeberg (2), and Levine (3) and was based on the ease of extraction of the polysaccharides from cartilage by alkali and on their resistance to extraction by water. Practically the entire...